Bruno Sportisse is a graduate of the École Polytechnique and chief engineer of the Corps des Ponts et Chaussées. He also holds a PhD in applied mathematics and a research habilitation.

His entire scientific career has been with or within Inria: after his PhD work devoted to high-dimensional dynamical systems, carried out under the supervision of Bernard Larrouturou, then Inria CEO (1996-1999), he coordinated an Inria Joint Research Action on numerical simulation for environmental applications (COMODE), before creating with Isabelle Herlin the CLIME Inria project team dedicated to data assimilation in 2003, while serving as director of the joint Ecole des Ponts-EDF R&D laboratory which he founded.

From 2008 to 2012, Bruno Sportisse was Director of Technology Transfer and Innovation at Inria. He set up numerous technology transfer support initiatives.

In 2012, he was appointed as the digital and innovation advisor to the French Minister of Higher Education and Research, Geneviève Fioraso, then, in 2013, as Deputy Chief of staff to the French Minister for Digital Economy, SMEs and innovation, Fleur Pellerin. Notably, he initiated and led the interministerial programme “New Deal for Innovation”, including the launch of the French Tech Initiative.

In 2014, Bruno Sportisse became the Executive Vice President of Thuasne, a mid-sized MedTech company, where he initiated the digital transformation of the company. In 2016, he started an entrepreneurial adventure that led to the creation, with Agnès Guerraz and Eric Gaussier as cofounders, of Skopai, a FinTech startup company combining artificial intelligence and natural language processing, and stemming out from the University of Grenoble-Alpes (LIG, Grenoble Lab for computer science).

In 2018, he was also tasked by the French Ministers Bruno Le Maire (Economy), Florence Parly (Defense), Frédérique Vidal (Higher Education, Research and Innovation) and Mounir Mahjoubi (Digital) with proposing the design and the implementation of a European Agency for Breakthrough Innovation , in conjunction with the creation of the European Innovation Council (EIC) within the next European R&D framework programme. In the same year, Bruno Sportisse was promoted to knight in the Order of Merit by the Ministry of Economy and Finance.